SINISA BJELIC, PI
see GOOGLE SCHOLAR for citations and impact assessment
ARTICLES (PEER-REVIEWED)
*corresponding author
2019
Panagiota S. Georgoulia, Guido Todde, Sinisa Bjelic*, Ran Friedman* (2019) The catalytic activity of Abl1 single and compound mutations: Implications for the mechanism of drug resistance mutations in chronic myeloid leukaemia, BBA general, https://www.sciencedirect.com/science/article/pii/S0304416519300170?via%3Dihub
2018
Ingemar André and Sinisa Bjelic* (2018) Computational assessment of folding energy landscapes in heterodimeric coiled coils, Proteins: Structure, Function, Bioinformatics, https://doi.org/10.1002/prot.25516
2015
Wijma, H.J., Floor, R.J., Bjelic S., Marrink, S.J, Baker, D, and Janssen, D.B. (2015) Enantioselective enzymes by computational design and in silico screening, Angewandte Chemie, 127, 3797-801.
2014
Liu, Y., Zhang, X., Tan, Y.L., Bhabha, G., Ekiert, D.C., Kipnis, Y., Bjelic, S., Baker, D., Kelly, J.W. (2014) De novo-designed enzymes as small-molecule-regulated fluorescence imaging tags and fluorescent reporters, JACS, 136, 13102-5.
2014
Liu, Y., Tan, Y.L., Zhang, X., Bhabha, G., Ekiert, D.C., Genereux, J.C., Cho, Y.H, Kipnis, Y., Bjelic, S., Baker, D., and Kelly, J.W. (2014) Small molecule probes to quantify the functional fraction of a specific protein in a cell with minimal folding equilibrium shifts, Proceedings of National Academy of Sciences, 111, 4449-54.
2014
Nivon, L.G., Bjelic, S., King, C., Baker, D. (2014) Automating human intuition for protein design, Proteins: Structure, Function & Bioinformatics, 82, 858-66.
2014
Bjelic, S., Kipnis, Y., Wang, L., Pianowski, Z., Vorobiev, S., Su, M., Seetharaman, J., Xiao, R., Kornhaber, G., Hunt, J.F., Tong, L., Hilvert, D., and Baker, D. (2014) Exploration of alternate catalytic mechanisms and optimization strategies for retroaldolase design, Journal of Molecular Biology, 426, 256-71.
2013
Bjelic, S., Nivon, L.G., Çelebi-Olçum, N., Kiss, G., Rosewall, C.F., Lovick, H.M., Ingalls, E.L., Gallaher, J.L., Seetharaman, J., Lew, S., Montelione, G.T., Hunt, J.F., Michael, F.E., Houk K.N., and Baker, D. (2013) Computational design of enone-binding proteins with catalytic activity for the Morita-Baylis-Hillman reaction, ACS Chemical Biology, 8, 749-57.
2011
Richter, F., Leaver-Fay, A., Khare, S.D., Bjelic, S., and Baker, D. (2011) De novo enzyme design using ROSETTA3, PLoS ONE, 6.
2008
Bjelic, S., Brandsdal, B.O., and Åqvist, J. (2008) Cold adaptation of citrate synthase enzyme, Biochmistry 47, 10049-10057.
2006
Bjelic, S., and Åqvist, J. (2006) Catalysis and linear free energy relationships in aspartic proteases, Biochemistry 45, 7709-23.
2004
Bjelic, S., and Åqvist, J. (2004) Computational prediction of structure, substrate binding mode, mechanism, and rate for a malaria protease with a novel type of active site, Biochemistry 43, 14521-14528.
2004
Åqvist, J., Wennerström, P., Nervall, M., Bjelic, S., and Brandsdal, B.O., (2004) Molecular dynamics simulations of water and biomolecules wit a Monte Carlo constant pressure algorithm, Chemical Physics Letters, 384, 288-294.
2004
Ersmark, K., Feierberg, I., Bjelic, S., Hamelink, E., Hackett, F., Blackman, M.J., Hulten, J., Samuelsson, B., Åqvist, J., and Hallberg, A. (2004) Potent inhibitors of the Plasmodium falciparum enzymes plasmepsin I and II devoid of cathepsin D inhibitory activity, Journal of Medicinal Chemistry, 47, 110-122.
2003
Ersmark, K., Feierberg, I., Bjelic, S., Hulten, J., Samuelsson, B., Åqvist, J., and Hallberg, A. (2003) C2-symmetric inhibitors of Plasmodium falciparum plasmepsin II: Synthesis and theoretical predictions, Bioorganic & Medicinal Chemistry, 11, 3723-3733.
REVIEW ARTICLES (PEER-REVIEWED)
2007
Bjelic, S., Nerval, M., Gutiérrez-de-Terán, H., Ersmark, K., Hallberg, A., and Åqvist, J. (2007) Computational inhibitor design against malaria plasmepsins, CMLS 64, 2285-305.